Siberian Journal of Life Sciences and Agriculture (Jun 2019)

FEATURES OF PRO- AND ANTIOXIDANT SYSTEMS OF ERYTHROCYTES OF PATIENTS WITH COLORECTAL CANCER

  • Yaroslava Igorevna Perepechay,
  • Olga Valentinovna Smirnova,
  • Nadezhda Mitrofanovna Titova,
  • Margarita Olegovna Glazkova,
  • Violetta ValeriSiberian Federal Universityevna Borisova,
  • Andrei Evgenievich Kurchenko,
  • Anna Andreevna Timofeeva,
  • Viktoria Alexandrovna Mishina,
  • Oksana Andreevna Efimova

DOI
https://doi.org/10.12731/2658-6649-2019-11-5-112-117
Journal volume & issue
Vol. 11, no. 5
pp. 112 – 117

Abstract

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In this paper, we study prooxidant and antioxidant processes in the erythrocytes of patients with colorectal cancer. Тhe state of the antioxidant system was assessed by the content of GSH, the activity of SOD, catalase, GPO, GST. The state of the prooxidant system was assessed by the level of diene conjugates and malonic dialdehyde. A decrease in the activity of antioxidant enzymes and the intensification of lipid peroxidation in patients with colorectal cancer has been shown.

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