Favorable pharmacokinetic and pharmacodynamic properties of gilteritinib in cerebrospinal fluid: a potential effective treatment in relapsing meningeal acute myeloid leukemia <i>FLT3</i>-ITD patients

• Nicolas Vignal,
• Loïs Kelly,
• Etienne Lengline,
• Aurélie Cabannes-Hamy,
• Justine Siavellis,
• David Ghez,
• Hélène Sauvageon,
• Thorsten Braun,
• Evelyne Jacqz-Aigrain,
• Milena Kohn,
• Philippe Rousselot,
• Alexandre Puissant,
• Emmanuel Raffoux,
• Samia Mourah,
• Lauriane Goldwirt

Affiliations

Nicolas Vignal

AP-HP, Hôpital Saint-Louis, Department of Pharmacology, Paris, France; INSERM U976, Université Paris Cité, Paris

Loïs Kelly

INSERM U944, Université Paris-Cité, Paris

Etienne Lengline

AP-HP, Hôpital Saint-Louis, Department of Haematology, Paris

Aurélie Cabannes-Hamy

CH Versailles, Department of Haemato-Oncology, Versailles

Justine Siavellis

AP-HP, Hôpital Avicenne, Department of Haematology, Paris

David Ghez

IGR, Department of Haematology, Villejuif

Hélène Sauvageon

AP-HP, Hôpital Saint-Louis, Department of Pharmacology, Paris, France; INSERM U976, Université Paris Cité, Paris

Thorsten Braun

AP-HP, Hôpital Avicenne, Department of Haematology, Paris

Evelyne Jacqz-Aigrain

AP-HP, Hôpital Saint-Louis, Department of Pharmacology, Paris

Milena Kohn

CH Versailles, Department of Haemato-Oncology, Versailles

Philippe Rousselot

CH Versailles, Department of Haemato-Oncology, Versailles

Alexandre Puissant

INSERM U944, Université Paris-Cité, Paris

Emmanuel Raffoux

AP-HP, Hôpital Saint-Louis, Department of Haematology, Paris

Samia Mourah

AP-HP, Hôpital Saint-Louis, Department of Pharmacology, Paris, France; INSERM U976, Université Paris Cité, Paris

Lauriane Goldwirt

AP-HP, Hôpital Saint-Louis, Department of Pharmacology, Paris, France; INSERM U976, Université Paris Cité, Paris