Cefotaxime induced generalized bullous fixed drug eruption - A case report

R. Manikandan; A. Porselvi; G.C. Keerthana; K. Vaishnavi; S. Girija; Murali Narasimhan; TM. Vijayakumar

Toxicology Reports (Jan 2018)

Cefotaxime induced generalized bullous fixed drug eruption - A case report

R. Manikandan,
A. Porselvi,
G.C. Keerthana,
K. Vaishnavi,
S. Girija,
Murali Narasimhan,
TM. Vijayakumar

Affiliations

R. Manikandan: Department of Pharmacy Practice, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, 603 203, Kanchipuram (Dt), Tamil Nadu, India
A. Porselvi: Department of Pharmacy Practice, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, 603 203, Kanchipuram (Dt), Tamil Nadu, India
G.C. Keerthana: Department of Pharmacy Practice, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, 603 203, Kanchipuram (Dt), Tamil Nadu, India
K. Vaishnavi: Department of Pharmacy Practice, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, 603 203, Kanchipuram (Dt), Tamil Nadu, India
S. Girija: Department of Pharmacy Practice, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, 603 203, Kanchipuram (Dt), Tamil Nadu, India
Murali Narasimhan: Department of Dermatology, SRM Medical College Hospital & Research Centre, SRM Institute of Science and Technology, Kattankulathur, 603 203, Kanchipuram (Dt), Tamil Nadu, India
TM. Vijayakumar: Department of Pharmacy Practice, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, 603 203, Kanchipuram (Dt), Tamil Nadu, India; Corresponding author at: Department of Pharmacy Practice, SRM College of Pharmacy, SRM Institute of Science and Technology, SRM Nagar, Kattankulathur, 603 203, India.

Journal volume & issue: Vol. 5
pp. 1011 – 1013

Abstract

Read online

Fixed drug eruption (FDE) is the most common cutaneous adverse drug reaction. Cefotaxime, a broad-spectrum third-generation cephalosporin, appeared to be a safe and effective therapy in greater than 90% of infections including cellulitis, abscesses and necrotizing ulcers of the skin and subcutaneous tissues but here we report a rare case of 36 years old female patient developed generalized bullous FDE after intravenous administration of Cefotaxime. Keywords: Cefotaxime, Fixed drug eruption, Antibiotic, Dermatology

Published in Toxicology Reports

ISSN: 2214-7500 (Online)
Publisher: Elsevier
Country of publisher: Ireland
LCC subjects: Medicine: Public aspects of medicine: Toxicology. Poisons
Website: http://www.journals.elsevier.com/toxicology-reports/

About the journal