Frontiers in Microbiology (Sep 2022)
Regulation of the cecal microbiota community and the fatty liver deposition by the addition of brewers’ spent grain to feed of Landes geese
- Ping Xu,
- Ping Xu,
- Ping Xu,
- Yuxuan Hong,
- Yuxuan Hong,
- Yuxuan Hong,
- Pinpin Chen,
- Pinpin Chen,
- Pinpin Chen,
- Xu Wang,
- Xu Wang,
- Xu Wang,
- Shijie Li,
- Shijie Li,
- Shijie Li,
- Jie Wang,
- Jie Wang,
- Jie Wang,
- Fancong Meng,
- Fancong Meng,
- Fancong Meng,
- Zutao Zhou,
- Zutao Zhou,
- Zutao Zhou,
- Deshi Shi,
- Deshi Shi,
- Deshi Shi,
- Zili Li,
- Zili Li,
- Zili Li,
- Shengbo Cao,
- Shengbo Cao,
- Shengbo Cao,
- Yuncai Xiao,
- Yuncai Xiao,
- Yuncai Xiao
Affiliations
- Ping Xu
- College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China
- Ping Xu
- State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China
- Ping Xu
- Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Huazhong Agricultural University, Wuhan, China
- Yuxuan Hong
- College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China
- Yuxuan Hong
- State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China
- Yuxuan Hong
- Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Huazhong Agricultural University, Wuhan, China
- Pinpin Chen
- College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China
- Pinpin Chen
- State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China
- Pinpin Chen
- Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Huazhong Agricultural University, Wuhan, China
- Xu Wang
- College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China
- Xu Wang
- State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China
- Xu Wang
- Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Huazhong Agricultural University, Wuhan, China
- Shijie Li
- College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China
- Shijie Li
- State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China
- Shijie Li
- Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Huazhong Agricultural University, Wuhan, China
- Jie Wang
- College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China
- Jie Wang
- State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China
- Jie Wang
- Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Huazhong Agricultural University, Wuhan, China
- Fancong Meng
- College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China
- Fancong Meng
- State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China
- Fancong Meng
- Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Huazhong Agricultural University, Wuhan, China
- Zutao Zhou
- College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China
- Zutao Zhou
- State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China
- Zutao Zhou
- Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Huazhong Agricultural University, Wuhan, China
- Deshi Shi
- College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China
- Deshi Shi
- State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China
- Deshi Shi
- Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Huazhong Agricultural University, Wuhan, China
- Zili Li
- College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China
- Zili Li
- State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China
- Zili Li
- Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Huazhong Agricultural University, Wuhan, China
- Shengbo Cao
- College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China
- Shengbo Cao
- State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China
- Shengbo Cao
- Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Huazhong Agricultural University, Wuhan, China
- Yuncai Xiao
- College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China
- Yuncai Xiao
- State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China
- Yuncai Xiao
- Key Laboratory of Preventive Veterinary Medicine in Hubei Province, Huazhong Agricultural University, Wuhan, China
- DOI
- https://doi.org/10.3389/fmicb.2022.970563
- Journal volume & issue
-
Vol. 13
Abstract
The effects of brewers’ spent grain (BSG) diets on the fatty liver deposition and the cecal microbial community were investigated in a total of 320 healthy 5-day-old Landes geese. These geese were randomly and evenly divided into 4 groups each containing 8 replicates and 10 geese per replicate. These four groups of geese were fed from the rearing stage (days 5–60) to the overfeeding stage (days 61–90). The Landes geese in group C (control) were fed with basal diet (days 5–90); group B fed first with basal diet in the rearing stage and then basal diet + 4% BSG in the overfeeding stage; group F first with basal diet + 4% BSG during the rearing stage and then basal diet in the overfeeding stage; and group W with basal diet + 4% BSG (days 5–90). The results showed that during the rearing stage, the body weight (BW) and the average daily gain (ADG) of Landes geese were significantly increased in groups F and W, while during the overfeeding stage, the liver weights of groups W and B were significantly higher than that of group C. The taxonomic structure of the intestinal microbiota revealed that during the overfeeding period, the relative abundance of Bacteroides in group W was increased compared to group C, while the relative abundances of Escherichia–Shigella and prevotellaceae_Ga6A1_group were decreased. Results of the transcriptomics analysis showed that addition of BSG to Landes geese diets altered the expression of genes involved in PI3K-Akt signaling pathway and sphingolipid metabolism in the liver. Our study provided novel experimental evidence based on the cecal microbiota to support the application of BSG in the regulation of fatty liver deposition by modulating the gut microbiota in Landes geese.
Keywords
- brewers’ spent grain
- Landes goose
- fatty liver
- cecal microbiota community
- differentially expressed gene
- transcriptomics