A diagnostic challenge – autoimmune encephalitis as paraneoplastic syndrome of ovarian teratoma. Current state of knowledge

Abstract

Autoimmune encephalitis (AE) is one of the paraneoplastic syndromes of ovarian teratoma. Insufficient knowledge about the evolution of the disease, as well as its manifestation in the form of non-specific clinical symptoms (such as significant deterioration of memory and cognitive functions of patients), is a common cause of a prolonged diagnostic process and delay in the introduction of targeted treatment. The aim of the study was to summarize the data available in the literature, as well as recent reports, to facilitate and accelerate the diagnosis of the syndrome and ensure better care for patients.

Keywords

• limbic encephalitis
• ovarian teratoma
• anti-nmda-receptor
• neuronal antigen