Case Reports in Oncology (Aug 2016)

Primary Cerebellar Neuroendocrine Tumors: Chimeras or Real Entities? A Case Report with a 6-Year Follow-Up

  • Claudio Vernieri,
  • Daniela Femia,
  • Sara Pusceddu,
  • Carlo Capella,
  • Juan Rosai,
  • Giuseppina Calareso,
  • Laura Concas,
  • Natalie Prinzi,
  • Giuseppe Lo Russo,
  • Filippo de Braud,
  • Roberto Buzzoni

DOI
https://doi.org/10.1159/000447771
Journal volume & issue
Vol. 9, no. 2
pp. 432 – 439

Abstract

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We report the case of a 38-year-old patient who was diagnosed with a cerebellar well-differentiated neuroendocrine tumor (WDNET) in 2009. At first glance, we believed that it was a metastasis from an unrecognized WDNET arising outside the cerebellum. However, despite a prolonged follow-up of 6 years, an extracranial WDNET has never been found. During this time, the tumor recurred locally twice, and the patient was treated with surgery and radiotherapy. At the moment, he enjoys good general conditions and his tumor is under control. Due to the histopathological characteristics and clinical behavior of the tumor, we believe that this is the first report to date of a primary cerebellar WDNET.

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