Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture

Stefanie G. Wohl; Nikolas L. Jorstad; Edward M. Levine; Thomas A. Reh

doi:10.1038/s41467-017-01624-y

Nature Communications (Nov 2017)

Müller glial microRNAs are required for the maintenance of glial homeostasis and retinal architecture

Stefanie G. Wohl,
Nikolas L. Jorstad,
Edward M. Levine,
Thomas A. Reh

Affiliations

Stefanie G. Wohl: Department of Biological Structure, University of Washington, Health Sciences Center
Nikolas L. Jorstad: Department of Biological Structure, University of Washington, Health Sciences Center
Edward M. Levine: Department of Ophthalmology and Visual Sciences, Vanderbilt University
Thomas A. Reh: Department of Biological Structure, University of Washington, Health Sciences Center

DOI: https://doi.org/10.1038/s41467-017-01624-y
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 15

Abstract

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Müller glia are a type of retinal glial cell important for maintaining retinal structure and implicated in response to retinal damage. Here the authors identify Brevican, a chondroitin sulfate proteoglycan, as a microRNA-modulated regulator of Müller glia function.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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