Therapeutic Advances in Infectious Disease (Apr 2023)

HTLV-1 uveitis in Colombia, an underrecognized complication of a hitherto neglected condition: a case series

  • Wilmer Villamil-Gomez,
  • Jaime R. Torres,
  • Juan Rojas-Hernández,
  • Jose Ignacio Restom Merlano,
  • Jairo Vergara-Corena,
  • Patricia Salgado,
  • Jorge Viloria-Ruiz,
  • Alvaro Castro,
  • Andrés Mauricio Cabrera Lasso,
  • Eduardo Gotuzzo

DOI
https://doi.org/10.1177/20499361231165864
Journal volume & issue
Vol. 10

Abstract

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Three Colombian patients with chronic HTLV-1 infection and severe intermediate and/or posterior uveitis are described. In one case, retinal ablation was necessary due to extensive peripheral degeneration, while the other two were successfully managed with local anti-inflammatory therapy. Gradual resolution of ocular findings was observed in all three patients on follow-up. Uveitis is a rarely recognized late complication of this infection, which represents a diagnostic and therapeutic challenge for clinicians in endemic countries. The real extension of HTLV-1 prevalence in Colombia and the frequency of its ophthalmologic complications remain to be determined.