Nature Communications (Nov 2019)

Pathways to cellular supremacy in biocomputing

  • Lewis Grozinger,
  • Martyn Amos,
  • Thomas E. Gorochowski,
  • Pablo Carbonell,
  • Diego A. Oyarzún,
  • Ruud Stoof,
  • Harold Fellermann,
  • Paolo Zuliani,
  • Huseyin Tas,
  • Angel Goñi-Moreno

DOI
https://doi.org/10.1038/s41467-019-13232-z
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 11

Abstract

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Synthetic biology uses cells as its computing substrate, often based on the genetic circuit concept. In this Perspective, the authors argue that existing synthetic biology approaches based on classical models of computation limit the potential of biocomputing, and propose that living organisms have under-exploited capabilities.