Nature Communications (Nov 2016)

An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy

  • Yichao Chen,
  • Rui Xia,
  • Yixian Huang,
  • Wenchen Zhao,
  • Jiang Li,
  • Xiaolan Zhang,
  • Pengcheng Wang,
  • Raman Venkataramanan,
  • Jie Fan,
  • Wen Xie,
  • Xiaochao Ma,
  • Binfeng Lu,
  • Song Li

DOI
https://doi.org/10.1038/ncomms13443
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 12

Abstract

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The use of immunostimulatory agents to enhance the efficacy of chemotherapy is a promising strategy in cancer therapy. Here, the authors report on a micellar nanoparticle that can effectively co-deliver chemo- and immunotherapeutics, resulting in an improved in vivoantitumour response.