New Secondary Metabolites from Marine-Derived Fungus <i>Talaromyces minnesotensis</i> BTBU20220184

Weiliang Wang; Jingjing Wang; Fuhang Song; Renming Jia; Long Wang; Xiuli Xu; Na Yang

doi:10.3390/md22060237

Marine Drugs (May 2024)

New Secondary Metabolites from Marine-Derived Fungus <i>Talaromyces minnesotensis</i> BTBU20220184

Weiliang Wang,
Jingjing Wang,
Fuhang Song,
Renming Jia,
Long Wang,
Xiuli Xu,
Na Yang

Affiliations

Weiliang Wang: Key Laboratory of Marine Mineral Resources and Polar Geology, Ministry of Education, School of Ocean Sciences, China University of Geosciences, Beijing 100083, China
Jingjing Wang: Key Laboratory of Marine Mineral Resources and Polar Geology, Ministry of Education, School of Ocean Sciences, China University of Geosciences, Beijing 100083, China
Fuhang Song: Key Laboratory of Geriatric Nutrition and Health, Ministry of Education of China, School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China
Renming Jia: Key Laboratory of Tropical Marine Ecosystem and Bioresource, Guangxi Key Laboratory of Beibu Gulf Marine Resources, Environment and Sustainable Development, Fourth Institute of Oceanography, Ministry of Natural Resources, Beihai 536000, China
Long Wang: State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China
Xiuli Xu: Key Laboratory of Marine Mineral Resources and Polar Geology, Ministry of Education, School of Ocean Sciences, China University of Geosciences, Beijing 100083, China
Na Yang: CAS Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China

DOI: https://doi.org/10.3390/md22060237
Journal volume & issue: Vol. 22, no. 6
p. 237

Abstract

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Six new compounds, talamitones A and B (1 and 2), demethyltalamitone B (3), talamiisocoumaringlycosides A and B (4 and 5), and talaminaphtholglycoside (6), together with six known compounds (7–12), were isolated from the marine-derived fungus Talaromyces minnesotensis BTBU20220184. The new structures were characterized by using HRESIMS and NMR. This is the first report of isocoumaringlycoside derivatives from a fungus of the Talaromyces genus. Compounds 5, 6, and 9 showed synergistic antibacterial activity against Staphylococcus aureus.

Published in Marine Drugs

ISSN: 1660-3397 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Biology (General)
Website: http://www.mdpi.com/journal/marinedrugs

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