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Disease Models & Mechanisms
(Jun 2023)
Vemurafenib improves muscle histopathology in a mouse model of LAMA2-related congenital muscular dystrophy
Ariany Oliveira-Santos,
Marisela Dagda,
Jennifer Wittmann,
Robert Smalley,
Dean J. Burkin
Affiliations
Ariany Oliveira-Santos
Department of Pharmacology, University of Nevada Reno, School of Medicine, Center for Molecular Medicine, Reno, NV 89557, USA
Marisela Dagda
Department of Pharmacology, University of Nevada Reno, School of Medicine, Center for Molecular Medicine, Reno, NV 89557, USA
Jennifer Wittmann
Department of Pharmacology, University of Nevada Reno, School of Medicine, Center for Molecular Medicine, Reno, NV 89557, USA
Robert Smalley
Department of Pharmacology, University of Nevada Reno, School of Medicine, Center for Molecular Medicine, Reno, NV 89557, USA
Dean J. Burkin
Department of Pharmacology, University of Nevada Reno, School of Medicine, Center for Molecular Medicine, Reno, NV 89557, USA
DOI
https://doi.org/10.1242/dmm.049916
Journal volume & issue
Vol. 16, no. 6
Abstract
Read online
No abstracts available.
Keywords
lama2-cmd
congenital muscular dystrophy
mdc1a
laminin-α2
tgf-β
mtor
vemurafenib
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