May Serum Creatine Kınase (CK) Level Be a Malnutrition Parameter In Patients Wıth End-Stage Kidney Failure?

Abstract

Aim: The aim of this study was to investigate the relationship between serum CK levels and malnutrition parameters in patients undergoing hemodialysis (HD) and peritoneal dialysis (PD) for end stage renal disease (ESRD).Methods: In this prospective study, 60 patients receiving HD and 30 patients receiving PD for ESRD were evaluated. The relationship between serum CK levels and Mini Nutritional Assessment (MNA) Test scores, albumin, C-Reactive Protein (CRP), arterial blood gas parameters, KT / V ratio, total body water, muscle mass, body mass index (BMI) and lean body mass (determined by Bioelectrical Impedance Analysis (BIA) were examined.Results: No correlation was found between CK levels and age, dialysis duration and Ca values in HD and PD patients (p> 0.05). A positive correlation was found between CK levels and MNA scores and triceps skinfold thickness, lean body mass, body muscle mass and BMI values of PD and HD patients, and a significant negative correlation between total body water values (p <0.001).Conclusions: It was determined that serum CK level was compatible with other parameters used in the determination and follow-up of nutritional disorder and sarcopenia in ESRD patients.

Keywords

• son dönem böbrek hastalığı
• biyoelektriksel empedans
• kreatin kinaz
• sarkopeni
• malnütrisyon
• end-stage renal disease
• bioelectrical impedance
• creatine kinase
• sarcopenia
• malnutrition