Acta Biomedica Scientifica (Nov 2015)
Interrelation between the system of complement, Tolllike receptors, CD antigens and cytokines in normal and pathological condition. Review
Abstract
The overview of publications of the last five years is devoted to currently described communicative relationships between complement system, antigens of CD class, Toll-like receptors, other pattern recognition receptors and recognition molecules (interleukins, other cytokines, lectins). Studied aspects of innate immunity system actions include cooperation and synergism; adaptive strategies of microbial and viral pathogens; using probiotic microorganisms; initiation, switching, amplification and termination of key pathways in host antipathogen strategies; approaches to creation of address mechanisms of treatments of diseases at the level of metabolome network communications; prospects for constructing combinative system preparations for medicine.