KHSRP loss increases neuronal growth and synaptic transmission and alters memory consolidation through RNA stabilization

Affiliations

Sarah L. Olguin: Department of Neurosciences, University of New Mexico School of Medicine
Priyanka Patel: Department of Biological Sciences, University of South Carolina
Courtney N. Buchanan: Department of Biological Sciences, University of South Carolina
Michela Dell’Orco: Department of Neurosciences, University of New Mexico School of Medicine
Amy S. Gardiner: Department of Neurosciences, University of New Mexico School of Medicine
Robert Cole: Department of Neuroscience, University of Kentucky
Lauren S. Vaughn: Department of Biological Sciences, University of South Carolina
Anitha Sundararajan: National Center for Genome Resources
Joann Mudge: National Center for Genome Resources
Andrea M. Allan: Department of Neurosciences, University of New Mexico School of Medicine
Pavel Ortinski: Department of Neuroscience, University of Kentucky
Jonathan L. Brigman: Department of Neurosciences, University of New Mexico School of Medicine
Jeffery L. Twiss: Department of Biological Sciences, University of South Carolina
Nora I. Perrone-Bizzozero: Department of Neurosciences, University of New Mexico School of Medicine

Abstract

KH-type splicing regulatory protein (KHSRP) regulates levels of several neuronal mRNAs linked to nervous system development and function.