Indian Journal of Ophthalmology (Jan 2014)
Aggressive posterior retinopathy of prematurity in infants ≥1500 g birth weight
- Gaurav Sanghi,
- Mangat R Dogra,
- Deeksha Katoch,
- Amod Gupta
Affiliations
- Gaurav Sanghi
- Mangat R Dogra
- Deeksha Katoch
- Amod Gupta
- DOI
- https://doi.org/10.4103/0301-4738.128639
- Journal volume & issue
-
Vol. 62,
no. 2
pp. 254 – 257
Abstract
In this retrospective case series, we report the spectrum and outcomes of aggressive posterior retinopathy of prematurity (APROP) in infants ≥1500 g birth weight. Twenty-nine eyes of 15 infants are included. All infants were referred from level I or II nurseries, received supplemental unmonitored oxygen for prolonged duration (>1 week) and had multiple systemic co-morbidities. Of the 29 eyes, 10 (34.5%) had zone 1 and 19 (65.5%) had posterior zone 2 disease. Twenty-five (86.2%) eyes had flat neovascularization and 4 (13.8%) eyes had brush like proliferation. We noticed large vascular loops in 10 (34.5%) eyes. After confluent laser photocoagulation, 22 (75.9%) eyes had a favorable outcome. The study concludes that APROP in heavier (≥1500 g birth weight) premature infants occurs mostly in posterior zone 2 with flat neovascularization and atypical features like large vascular loops. Supplemental unmonitored oxygen for prolonged duration and multiple systemic co-morbidities could be a contributing factor.
Keywords
- Blindness
- cataract
- eye lens
- risk factors
- treatment of cataract
- Low vision care
- multiple disabilities and visual impairment
- reading performance
- Accommodation
- presbyopia
- supraciliary segment implants
- Amblyopia
- citicoline
- patching
- Corneal endothelium
- human corneal endothelial precursor cells
- in vitro expansion
- sphere forming assay
- thermo-reversible gelation polymer
- transportation
- Endophthalmitis
- explantation
- fungal
- intraocular lens
- postoperative
- recurrent
- Colour perception
- learning disabilities
- school children
- stereo acuity
- testability
- visual acuity
- Contracted socket
- dermis fat graft
- porous orbital implant
- reconstruction
- Glucose
- in vitro anticataract
- lens
- Moringa oliefera
- ′BARC I-125 Ocu-Prosta seeds′
- choroidal melanoma
- ciliary body melanoma
- Episcleral plaque brachytherapy
- retinal angioma
- retinoblastoma
- vasoproliferative tumor
- Congenital glaucoma
- gonioscopy
- Retcam
- Acoustic features
- A-scan
- B-scan
- choroidal mass
- ultrasound biomicroscopy
- Cataract surgery
- education
- informed consent
- multimedia
- rural health
- Lagophthalmos
- silicone sling
- temporalis muscle
- Contrast sensitivity function
- disability
- function peak
- multiple sclerosis
- spatial frequency
- Congenital cataract
- developmental cataract
- outcome
- vision function
- Bacterial
- extracellular enzymes
- fungal
- keratitis
- toxins
- Exotropic Duane retraction syndrome
- periosteal fixation
- strabismus surgery
- vertical rectus transposition
- Descemet′s stripping endothelial keratoplasty
- complications
- donor dislocation
- endothelial cell loss
- graft failure
- management
- Glaucoma
- glaucoma experimental
- parapapillary atrophy
- Juvenile open angle glaucoma
- juvenile glaucoma
- primary trabeculectomy
- trabeculectomy in young
- Collagen cross linking
- keratoconus
- topography guided custom ablation treatment
- topography guided photoablation
- Azithromycin
- chloramphenicol
- fluoroquinolone
- non-chlamydia conjunctival bacteria
- Ethiopia
- Cataract surgery
- near vision
- prevalence of blindness
- visual outcome
- Congenital aniridia
- descemet stripping endothelial keratoplasty
- progressive anterior segment fibrosis syndrome
- Early removal
- high doses of steroids
- mimics microbial keratitis
- stingers
- Childhood corneal opacity
- congenital hereditary endothelial dystrophy
- corneal edema
- Descemet′s stripping endothelial keratoplasty
- endothelial keratoplasty
- pediatric keratoplasty
- Aggressive posterior retinopathy of prematurity
- APROP
- atypical ROP
- developing country
- heavier infants
- neonatal care
- oxygen induced retinopathy
- retinopathy of prematurity
- ROP
- zone 1 ROP