Nature Communications (Jun 2022)

Laboratory evolution of synthetic electron transport system variants reveals a larger metabolic respiratory system and its plasticity

  • Amitesh Anand,
  • Arjun Patel,
  • Ke Chen,
  • Connor A. Olson,
  • Patrick V. Phaneuf,
  • Cameron Lamoureux,
  • Ying Hefner,
  • Richard Szubin,
  • Adam M. Feist,
  • Bernhard O. Palsson

DOI
https://doi.org/10.1038/s41467-022-30877-5
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 9

Abstract

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The bacterial respiratory electron transport system (ETS) is branched to allow condition-specific modulation of energy metabolism. Here the authors examine the systems level properties of aerobic electron transport system using adaptive laboratory evolution and multi-omics analyses.