Атеросклероз (Dec 2014)
Prevalence of dyslipidemia in case of diabetes mellitus in Novosibirsk within patients 45-69 age
Abstract
Goals. To assess the prevalence of dyslipidemia with increased glycemia fasted and diabetes mellitus(DM) in population with age range from 45 to 69 years of the large industrial center of Western Siberia – Novosibirsk city. Assess the risk of cardiovascular mortality in patients with diabetes and dyslipidemia. Materials and methods: During the period from 2003 to 2005 within the frameworks of population screening at HAPIEE project 9360 people were examined inclusive of 4268 men (46 %) and 5094 women (54 %). Examination record included: anthropometry, biochemical parameters definition. Hyperglycemia was diagnosed when the blood plasma fated glucose parameters were ≥ 6.1mmol/L in compliances with NCEP ATP III, 2001 criteria and ≥ 5.6 mmol/L in compliance with criteria IDF, 2005, IDF and AHA/NHLBI (2009). TG of dyslipidemia was equal to ≥1.7 mmol/L, HDL content was < 1.0 mmol/L for men and <1.3 mmol/L for women (NCEPATP III, 2001). The DM was diagnosed when blood glucose fasted levels were equal to ≥ 7.0 mmol/L (WHO, 1999) and when patients with diagnosed diabetes mellitus in anamnesis had normoglycemia. Statistical processing of results was carried out with the help of program package SPSS. Results: In Siberian population aged 45–69 for the patients with diabetes mellitus the prevalence of dyslipidemia is rather high: hyper-TG comprised 60,8 %, 59,8 % at men sampling and 61.7 % at women sampling. Chance of developing cardiovascular mortality in the presence giperTG or gipoHS-HDL and SD 2-fold higher than in patients with giperTG or gipoHS-HDL without DM. Conclusion: In Siberian population aged 45–69 years for patients with diabetes mellitus the dyslipidemia prevalence is rather high. Chance of developing cardiovascular mortality in the presence giperTG or gipoHS-HDL and SD 2-fold higher than in patients with giperTG or gipoHS-HDL without DM.
