A study on high ApoB and LDL levels in people attending a tertiary hospital in Coimbatore, India

Abstract

Background: It is estimated that around 17.9 million people die each year of cardiovascular disease. High LDL is an important risk factor for coronary artery disease. Apolipoprotein B (ApoB) is the primary apolipoprotein of chylomicrons, VLDL, IDL, and LDL. Increased Apo B levels and LDL levels are known to cause atherosclerotic coronary artery disease. Aim and Objectives: To measure LDL and Apo B levels of adult people and to calculate the prevalence of high ApoB and LDLin Coimbatore region. Material and Methods: This was a study done for a period of 3 months in 500 people attending a tertiary hospital in Coimbatore, Tamilnadu. Patients on statins, critically ill patients, pregnant women, and lactating women were excluded. ApoB and LDL levels were measured and the percentage of increased levels of the same was calculated. Results: Out of 500 people studied, 52.87% of the population had high LDL. About 45.76% of the males and 56.49% of the women had high LDL. Out of the study subjects, 4.33% of the people had high ApoB level. Pearson's correlation revealed 'r' value as 1, thereby indicating a positive correlation between ApoB and LDL. Conclusion: This study showed that around 50% of study subjects had high LDL levels and 4% had high ApoB levels, and there was a positive correlation between the two.

Keywords

• apo-b
• ldl
• cardiovascular disease
• atherosclerosis
• dyslipidemia