CuO Nanocatalyzed Improved Synthesis of Some 2- Aminopyrimidines

Abstract

An effective and simple method for the synthesis of substituted 2- aminopyrimidines has been developed using chalcones, guanidine nitrate and aqueous sodium hydroxide in the presence of CuO nanoparticle as catalyst. The developed strategy has various advantages such as short reaction time, improved yields and the catalyst used is recyclable and inexpensive. DOI: http://dx.doi.org/10.17807/orbital.v13i3.1621

Keywords

• Chalcones
• CuO nanocatalyst
• Guanidine nitrate
• Pyrimidine