Chlorine Atoms of an Aripiprazole Molecule Control the Geometry and Motion of Aripiprazole and Deschloro-aripiprazole in Subdomain IIIA of Human Serum Albumin

• Akito Kawai,
• Yoshihiro Kobashigawa,
• Kenshiro Hirata,
• Hiroshi Morioka,
• Shuhei Imoto,
• Koji Nishi,
• Victor Tuan Giam Chuang,
• Keishi Yamasaki,
• Masaki Otagiri

Affiliations

Akito Kawai

Fujita Health University School of Medicine, Toyoake, Aichi, Japan

Yoshihiro Kobashigawa

Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan

Kenshiro Hirata

Faculty of Pharmaceutical Sciences, Sojo University, Kumamoto, Japan

Hiroshi Morioka

Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan

Shuhei Imoto

Faculty of Pharmaceutical Sciences, Sojo University, Kumamoto, Japan

Koji Nishi

Faculty of Pharmaceutical Sciences, Sojo University, Kumamoto, Japan

Victor Tuan Giam Chuang

Discipline of Pharmacy, Curtin Medical School, Faculty of Health Sciences, Curtin University, Perth, Western Australia, Australia

Keishi Yamasaki

Faculty of Pharmaceutical Sciences, Sojo University, Kumamoto, Japan

Masaki Otagiri

Faculty of Pharmaceutical Sciences, Sojo University, Kumamoto, Japan