Quinone and Hydroquinone Metabolites from the Ascidians of the Genus Aplidium

Abstract

Ascidians of the genus Aplidium are recognized as an important source of chemical diversity and bioactive natural products. Among the compounds produced by this genus are non-nitrogenous metabolites, mainly prenylated quinones and hydroquinones. This review discusses the isolation, structural elucidation, and biological activities of quinones, hydroquinones, rossinones, longithorones, longithorols, floresolides, scabellones, conicaquinones, aplidinones, thiaplidiaquinones, and conithiaquinones. A compilation of the 13C-NMR spectral data of these compounds is also presented.

Keywords

• ascidian secondary metabolites
• structure elucidation
• bioactivity
• 13C-NMR spectral data
• quinones
• hydroquinones