A new approach to the facile synthesis of 1,8-dioxooctahydroxanthene using nano-TiO2/ CNT as an efficient catalyst

Abstract

1,8-dioxooctahydroxanthene derivatives have received considerable attention due to their valuable biological and medicinal properties such as anticoagulant, antispasmodic, diuretic, and anti-cancer activities. 1,8-dioxooctahydroxanthene derivatives have strong relaxing activity on blood vessels, cardiac muscles, and smooth muscles. The present study reports the easy synthesis of 1,8-dioxooctahydroxanthene derivatives using aldehydes and dimedon in the presence of nano-TiO2/ CNT as an efficient catalyst.

Keywords

• multicomponent reactions (mcrs)
• nano-tio2/ cnt
• xanthenes derivatives
• one-pot