A case of recalcitrant silicone granuloma treated with adalimumab: A case report

Orli M Silverberg; Benoit M Cyrenne; David Croitoru; Matthew K Sandre; Kucy Pon

doi:10.1177/2050313X221093444

SAGE Open Medical Case Reports (May 2022)

A case of recalcitrant silicone granuloma treated with adalimumab: A case report

Orli M Silverberg,
Benoit M Cyrenne,
David Croitoru,
Matthew K Sandre,
Kucy Pon

Affiliations

Orli M Silverberg: Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada
Benoit M Cyrenne: Division of Dermatology, Women’s College Hospital, Toronto, ON, Canada
David Croitoru: Division of Dermatology, Department of Medicine, University of Toronto, Toronto, ON, Canada
Matthew K Sandre: Division of Dermatology, Department of Medicine, University of Toronto, Toronto, ON, Canada
Kucy Pon: Division of Dermatology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada

DOI: https://doi.org/10.1177/2050313X221093444
Journal volume & issue: Vol. 10

Abstract

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Liquid silicone is a relatively inexpensive injectable used for soft tissue augmentation. Injection of silicone is associated with a risk of delayed granuloma formation associated with elevated levels of tumour necrosis factor-α. We report a case of recalcitrant silicone granulomas following facial injections of silicone successfully treated with tumour necrosis factor-α blockade. Our case, as well as previous reports, demonstrates the effectiveness of this therapy for the treatment of foreign body granulomas from due to silicone.

Published in SAGE Open Medical Case Reports

ISSN: 2050-313X (Online)
Publisher: SAGE Publishing
Country of publisher: United States
LCC subjects: Medicine: Medicine (General)
Website: https://journals.sagepub.com/home/sco

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