Nature Communications (Apr 2021)

An integrative analysis of the age-associated multi-omic landscape across cancers

  • Kasit Chatsirisupachai,
  • Tom Lesluyes,
  • Luminita Paraoan,
  • Peter Van Loo,
  • João Pedro de Magalhães

DOI
https://doi.org/10.1038/s41467-021-22560-y
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 17

Abstract

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Our understanding of the age-related molecular alterations in cancer is still limited. Here, the authors perform a pan-cancer analysis of age-associated genomic, transcriptomic, and epigenetic alterations, linking age-related gene expression changes to age-related DNA methylation alterations