Analysis on the risk factors of bacterial meningitis complicated with subdural effusion

Abstract

Objective To investigate the risk factors of bacterial meningitis complicated with subdural effusion. Methods The clinical data of children with bacterial meningitis in our hospital were collected and analyzed retrospectively. Logistic regression analysis was used to investigate the risk factors for subdural effusion. Results A total of 128 cases were divided into control group (N = 64) and subdural effusion group (N = 64). There was no significant difference on serum erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and white blood cell (WBC) between 2 groups (P > 0.05, for all). Compared with control group, cerebrospinal fluid (CSF) WBC (Z = 3.126, P = 0.003), CSF protein (Z = 4.928, P = 0.000) and serum procalcitonin (PCT; Z = 2.823, P = 0.007) in subdural effusion group were significantly higher, while CSF glucose (t = 2.166, P = 0.033) was significantly lower. After treatment, CSF WBC (Z = 2.467, P = 0.012) in subdural effusion group was still significantly higher than that of control group, and CSF glucose (t = 4.938, P = 0.000) was still significantly lower. Logistic regression analysis showed that WBC in CSF (P = 0.027), CSF protein (P = 0.002) and serum PCT (P = 0.014) were independent risk factors for bacterial meningitis complicated with subdural effusion. Conclusions CSF examination of children with bacterial meningitis reveals significant increase of CSF WBC, CSF protein and serum PCT, suggesting concurrent subdural effusion is easily occurred. DOI: 10.3969/j.issn.1672-6731.2015.08.012

Keywords

• Meningitis, bacterial
• Subdural effusion
• Risk factors
• Regression analysis
• Children