Face of the giant panda sign in Wilson disease

Abstract

Wilson disease usually presents with neurologic or hepatic manifestations. Magnetic resonance imaging (MRI) of the brain is very informative in diagnosiing of this disease, especially in patients with neurological features. High T2 signal intensity in the corpus striatum is the most commonly encountered MRI finding. The 'face of the giant panda' sign is seen on axial T2-weighted MRI, and results from abnormal signal intensities in the midbrain. Though uncommon, the sign is considered as the pathognomonic MRI sign of Wilson disease.

Keywords

• Face of panda sign
• Wilson disease
• MRI