7- OXIDATIVE ASSAULT DURING MAGNETIC RESONANCE IMAGING EXAMINATION

Abstract

Saad S Hammadi*, Salman K Ajlan@, Asal B. Shindi# & Abdul-Sattar J Yousof% *MB,ChB, FICMS, Professor, Department of Medicine. @MB,ChB, MSc, Assist Professor, Department of Biochemistry. #MB,ChB, MSc, Assist Professor, Department of Surgery College of Medicine, University of Basrah, Basrah, IRAQ. %FICMS, Department of Medicine, Al-Faiha General Hospital, Basrah, IRAQ. Address of Correspondence: Dr Saad S. Hammadi. Department of Medicine, College of Medicine, University of Basrah, Basrah, IRAQ. Abstract This study aimed to evaluate the degree of oxidative stress associated with magnetic resonance imaging (MRI) examination. Serum malondialdehyde (MDA) levels were estimated in 70 patients, 44 males and 26 females, 16-70 years of age underwent MRI examination for various reasons. There was an overall increase in serum MDA level following MRI examination with overall mean difference between pre- and post- MRI examination MDA level of 0.066 ±0.110 Mmole /l (P=65 were 0.05). It is concluded that MRI examination is associated with significant free radical activity reflected by marked elevation of serum MDA levels. This implies that MRI examination may impose an oxidative assault which in turn, may be of clinical significance in elderly patients in particular.

Keywords

• oxidative assault
• during magnetic
• resonance imaging