Педиатрическая фармакология (Oct 2018)

Innovations in the Therapy of Atopic Dermatitis Complicated by a Secondary Infection

  • Nikolay N. Murashkin,
  • Alexander I. Materikin,
  • Eduard T. Ambarchian,
  • Roman V. Epishev,
  • Dmitriy V. Fedorov

DOI
https://doi.org/10.15690/pf.v15i4.1946
Journal volume & issue
Vol. 15, no. 4
pp. 318 – 323

Abstract

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Reduced skin barrier properties in patients with atopic dermatitis (AtD) are largely caused by microbiome changes and extensive Staphylococcus aureus colonisation of the skin. In this regard, the integument of patients with AtD requires constant care and the use of various emollients. The inclusion of lysates of non-pathogenic microorganisms and prebiotics in the composition of emollients ensures the normalisation of the microbiome composition and the immunological barrier of the skin. The article presents the results of our own observations on the application of two cosmetic scin-care products for damaged skin with vitamin F in children with AtD complicated by a secondary infection, while the composition of one of the products is additionally enriched with ceramides and prebiotics. The safety and high efficacy of both products have been shown, however, the presence of ceramides and prebiotics in the emollient composition makes it possible to achieve a marked decrease in the degree of S. aureus colonisation of the skin.

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