Antihyperlipidaemic Activities of Agriophyllum squarrosum (L.) Moq. in vivo

Abstract

Agriophyllum squarrosum (L) Moq. is medicine herb used as a traditional Mongolian drug. Its pharmacological effi cacy studies are rarely reported. In the present study, we tested and confi rmed the antihyperlipidaemic activity of A. squarrosum and its extracts in rats for the fi rst time. The results of the antihyperlipidaemic experiment in vivo showed that A. squarrosum and its extracts had signifi cant lipid-lowering activities. The signifi cances of A. squarrosum and its extracts on decreasing blood levels of total cholesterol, triglyceride, and low density lipoprotein cholesterol were equal to that of simvastatin, which is a drug for the treatment of hyperlipidaemic.

Keywords

• Agriophyllum squarrosum; animal experiment; lipidlowering activity