Prolonged febrile illness due to CTX-M-15 extendedspectrum β-lactamase-producing <i>Klebsiella pneumoniae</i> infection in Nigeria

Abstract

We report on an 8-year-old patient with septicaemia unresponsive to therapy for five weeks. Undetected, extended-spectrum β-lactamase (ESBL) production by the infecting Klebsiella strain was regarded as responsible for treatment failure. Intravenously administered imipenem during the sixth week led to sustained resolution of fever. Resource-limited hospitals can incur prohibitive costs from ESBL-producer infections because of diagnostic limitations and consequent treatment failure involving prolonged supportive therapy.

Keywords

• septicaemia
• CTX-M-15
• Klebsiella pneumoniae
• Nigeria