Case Reports in Dermatology (Feb 2019)

Generalized Molluscum Contagiosum Successfully Treated with Interferon-Alpha in a Patient with Folliculotropic Mycosis Fungoides

  • Rutger C. Melchers,
  • Rein Willemze,
  • Patricia M. Jansen,
  • Joost S.P. Vermaat,
  • Maarten H. Vermeer,
  • Koen D. Quint

DOI
https://doi.org/10.1159/000497349
Journal volume & issue
Vol. 11, no. 1
pp. 52 – 56

Abstract

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We present the case of a 50-year-old patient with folliculotropic mycosis fungoides (FMF) unresponsive to retinoids and the chemotherapeutic regimens CHOP, gemcitabine, and brentuximab-vedotin. During immunosuppressive therapy, the patient developed extensive progressive molluscum contagiosum. The mollusca did not respond to topical imiquimod but showed a swift complete response to interferon-alpha 2a (IFNa). Recently, the patient started with alemtuzumab as induction therapy for an allogenic stem cell transplantation and simultaneously continued IFNa therapy.

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