Química Nova (Jul 1998)

Sistemas transportadores de drogas Drug delivery systems

  • Maria Luiza C. Montanari,
  • Carlos Alberto Montanari,
  • Dorila Piló-Veloso,
  • A. E. Beezer,
  • J. C. Mitchell

DOI
https://doi.org/10.1590/S0100-40421998000400017
Journal volume & issue
Vol. 21, no. 4
pp. 470 – 476

Abstract

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Drug delivery system controls the distribution of drugs for optimal therapeutic efficacy. The complex of higly active drugs with macromolecular carriers seems to offer a promising way to optimize their delivery. Dendrimers can be used as drug delivery system and this paper addresses the effectivenes of the approach. The host-guest system improves the solubility of hydrazides and mesoionic 1,3,4-thiadiazolium-2-aminide compounds.

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