S191: CALRETICULIN-MUTATED HEMATOPOIETIC CELLS ARE VULNERABLE TO THE COMBINED INHIBITION OF THE PROTEASOME AND THE IRE1A-XBP1 AXIS OF THE UNFOLDED PROTEIN RESPONSE

• J. S. Jutzi,
• A. E. Marneth,
• M. J. Jimenez-Santos,
• A. Guerra-Moreno,
• S. A. Myers,
• S. A. Carr,
• P. van Galen,
• F. Al-Shahrour,
• A. S. Nam,
• A. Mullally

Affiliations

J. S. Jutzi

1 Division of Hematology, Department of Medicine, Brigham and Women’s Hospital, Boston, United States of America

A. E. Marneth

1 Division of Hematology, Department of Medicine, Brigham and Women’s Hospital, Boston, United States of America

M. J. Jimenez-Santos

2 Bioinformatics Unit, Structural Biology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain

A. Guerra-Moreno

1 Division of Hematology, Department of Medicine, Brigham and Women’s Hospital, Boston, United States of America

S. A. Myers

3 The Broad Institute of MIT and Harvard, Cambridge

S. A. Carr

3 The Broad Institute of MIT and Harvard, Cambridge

P. van Galen

1 Division of Hematology, Department of Medicine, Brigham and Women’s Hospital, Boston, United States of America

F. Al-Shahrour

5 Bioinformatics Unit, Structural Biology Programme, Spanish National Cancer Research Centre (CNIO), Madrid

A. S. Nam

6 Weill Cornell Medicine, New York, United States of America

A. Mullally

1 Division of Hematology, Department of Medicine, Brigham and Women’s Hospital, Boston, United States of America