Psoriasis and Hashimoto's thyroiditis in a child with down syndrome

Abstract

Down syndrome (DS), or trisomy 21, is the most common chromosomal disorder. DS has been associated with autoimmune diseases including autoimmune thyroiditis, Type 1 diabetes mellitus, celiac disease, autoimmune chronic active hepatitis, alopecia, vitiligo, hypoparathyroidism, psoriasis, and psoriatic arthritis. To our knowledge, we herein report the first concurrence of psoriasis and Hashimoto's thyroiditis in an individual with DS, emphasizing the predisposition of DS individuals to autoimmune diseases.

Keywords

• Autoimmune diseases
• autoimmunity
• Down syndrome
• Hashimoto's thyroiditis
• psoriasis