Nature Communications (Sep 2022)

Microgel reinforced zwitterionic hydrogel coating for blood-contacting biomedical devices

  • Mengmeng Yao,
  • Zhijian Wei,
  • Junjin Li,
  • Zhicheng Guo,
  • Zhuojun Yan,
  • Xia Sun,
  • Qingyu Yu,
  • Xiaojun Wu,
  • Chaojie Yu,
  • Fanglian Yao,
  • Shiqing Feng,
  • Hong Zhang,
  • Junjie Li

DOI
https://doi.org/10.1038/s41467-022-33081-7
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 13

Abstract

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Zwitterionic hydrogels are nonfouling and hemocompatibility but several key challenges such as weak mechanical strength and low adhesion hamper their application as coating materials for devices. Here, the authors report a microgel reinforced zwitterionic hydrogel with excellent mechanical robustness and anti-swelling properties.