Aspergillus fumigatus Strain-Specific Conidia Lung Persistence Causes an Allergic Broncho-Pulmonary Aspergillosis-Like Disease Phenotype

Jane T. Jones; Ko-Wei Liu; Xi Wang; Caitlin H. Kowalski; Brandon S. Ross; Kathleen A. M. Mills; Joshua D. Kerkaert; Tobias M. Hohl; Lotus A. Lofgren; Jason E. Stajich; Joshua J. Obar; Robert A. Cramer

doi:10.1128/mSphere.01250-20

mSphere (Feb 2021)

Aspergillus fumigatus Strain-Specific Conidia Lung Persistence Causes an Allergic Broncho-Pulmonary Aspergillosis-Like Disease Phenotype

Jane T. Jones,
Ko-Wei Liu,
Xi Wang,
Caitlin H. Kowalski,
Brandon S. Ross,
Kathleen A. M. Mills,
Joshua D. Kerkaert,
Tobias M. Hohl,
Lotus A. Lofgren,
Jason E. Stajich,
Joshua J. Obar,
Robert A. Cramer

Affiliations

Jane T. Jones: Geisel School of Medicine, Department of Microbiology and Immunology, Dartmouth, Hanover, New Hampshire, USA
Ko-Wei Liu: Geisel School of Medicine, Department of Microbiology and Immunology, Dartmouth, Hanover, New Hampshire, USA
Xi Wang: Geisel School of Medicine, Department of Microbiology and Immunology, Dartmouth, Hanover, New Hampshire, USA
Caitlin H. Kowalski: Geisel School of Medicine, Department of Microbiology and Immunology, Dartmouth, Hanover, New Hampshire, USA
Brandon S. Ross: Geisel School of Medicine, Department of Microbiology and Immunology, Dartmouth, Hanover, New Hampshire, USA
Kathleen A. M. Mills: Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Joshua D. Kerkaert: Geisel School of Medicine, Department of Microbiology and Immunology, Dartmouth, Hanover, New Hampshire, USA
Tobias M. Hohl: ORCiD; Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Lotus A. Lofgren: Department of Microbiology and Plant Pathology, University of California Riverside, Riverside, California, USA
Jason E. Stajich: ORCiD; Department of Microbiology and Plant Pathology, University of California Riverside, Riverside, California, USA
Joshua J. Obar: ORCiD; Geisel School of Medicine, Department of Microbiology and Immunology, Dartmouth, Hanover, New Hampshire, USA
Robert A. Cramer: ORCiD; Geisel School of Medicine, Department of Microbiology and Immunology, Dartmouth, Hanover, New Hampshire, USA

DOI: https://doi.org/10.1128/mSphere.01250-20
Journal volume & issue: Vol. 6, no. 1

Abstract

Read online

Allergic broncho-pulmonary aspergillosis (ABPA) patients often present with long-term colonization of Aspergillus fumigatusin vivo

Published in mSphere

ISSN: 2379-5042 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/msphere

About the journal