Cord Blood Vitamin D Level in Neonates of Preeclamptic Mothers

Abstract

INTRODUCTION[|]Vitamin D deficiency may play a role in the pathogenesis of preeclampsia by causing abnormal placental implantation and by affecting the inflammatory response. The aim of this study was to compare the cord blood vitamin D level in neonates born to preeclamptic mothers with that of a control group of newborns whose mothers were not preeclamptic.[¤]METHODS[|]The preeclamptic group was made up of newborns of mothers classified as having moderate to severe preeclampsia. Neonates of a similar gestational age and birth weight born to normotensive mothers comprised the control group. The cord blood vitamin D level of both groups of newborns was measured and the results were statistically compared. [¤]RESULTS[|]Sixty neonates born to preeclamptic mothers and 47 born to normotensive mothers were included in the study. The mean serum vitamin D level of the study group was 12.62+-5.43 ng/mL and 12.85+-5.56 ng/mL in the control group. The percentage of those determined to have a serum vitamin D level <20 ng/mL in the study and the control groups was 89.5% and 88.9%, respectively. The serum magnesium level in the study group was statistically greater than that observed in the control group (p<0.001).[¤]DISCUSSION AND CONCLUSION[|]The cord blood vitamin D level of those born to preeclamptic mothers was not found to be statistically different when compared with the vitamin D level of neonates of normotensive mothers.[¤]

Keywords

• cord blood
• preeclampsia; vitamin d.