Bulletin of the National Research Centre (Jun 2023)

Methicillin-resistant Staphylococcus aureus: novel treatment approach breakthroughs

  • Balaji Maddiboyina,
  • Harekrishna Roy,
  • M. Ramaiah,
  • C. N. Sarvesh,
  • Sahasra Hanuman Kosuru,
  • Ramya Krishna Nakkala,
  • Bhabani Shankar Nayak

DOI
https://doi.org/10.1186/s42269-023-01072-3
Journal volume & issue
Vol. 47, no. 1
pp. 1 – 15

Abstract

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Abstract Background Methicillin-resistant Staphylococcus aureus (MRSA) is a common bacterial infection that is a significant source of illness and mortality globally. The advancements in antibiotic therapies continue to be the critical aspects of treating bacterial infections, and their usage has lowered patient mortality and raised life expectancy. Main body of the abstract The ideal treatments for MRSA remain challenging, and the quest for new antibiotic targets and advanced drug delivery systems with safety profiles is necessary to ensure treating MRSA infections adequately in the future. Short conclusion This article primarily focuses on different therapeutic medications and their modes of action for general microbial infections and goes through the latest developments in novel drug delivery technologies, such as hydrogels, lipid particles, nanocarriers, and polymers for MRSA treatment. Graphical Abstract

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