Persistent replication of SARS-CoV-2 in a severely immunocompromised patient treated with several courses of remdesivir

Abstract

Microbiological response of SARS-CoV-2 to remdesivir in immunocompromised patients has not been evaluated. We present the case of a severely immunocompromised patient with persistent replication of SARS-CoV-2, who required different courses of remdesivir. Short courses of remdesivir might be insufficient in immunocompromised patients due to prolonged viral clearance.

Keywords

• Remdesivir
• COVID-19
• SARS-CoV-2
• Immunosuppression
• Lymphoma