Communications Biology (Jan 2021)

AAV1 is the optimal viral vector for optogenetic experiments in pigeons (Columba livia)

  • Noemi Rook,
  • John Michael Tuff,
  • Sevim Isparta,
  • Olivia Andrea Masseck,
  • Stefan Herlitze,
  • Onur Güntürkün,
  • Roland Pusch

DOI
https://doi.org/10.1038/s42003-020-01595-9
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 16

Abstract

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Rook et al. establish a viral gene transfer system to perform optogenetics in pigeons. They deliver ChR2 via AAV1 into the visual entopallium and show its behavioral relevance for contrast perception, verifying the applicability of optogenetics in an avian species.