mBio (Apr 2021)

Extent of Cytomegalovirus Replication in the Human Host Depends on Variations of the HLA-E/UL40 Axis

  • Hannes Vietzen,
  • Timo Rückert,
  • Svenja Hartenberger,
  • Claudia Honsig,
  • Peter Jaksch,
  • Silvana Geleff,
  • Quirin Hammer,
  • Chiara Romagnani,
  • Maia Segura-Wang,
  • Elisabeth Puchhammer-Stöckl

DOI
https://doi.org/10.1128/mBio.02996-20
Journal volume & issue
Vol. 12, no. 2

Abstract

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Infection with human cytomegalovirus (HCMV) is associated with substantial morbidity in immunosuppressed patients and after congenital infections. Therefore, development of a vaccine against HCMV is a main public health priority.