Journal of Veterinary Internal Medicine (Jan 2024)

Acute adrenal necrosis in a young female cat

  • Rebecca A. Manson,
  • Tara N. Hammond,
  • Julie E. Callahan Clark

DOI
https://doi.org/10.1111/jvim.16926
Journal volume & issue
Vol. 38, no. 1
pp. 346 – 350

Abstract

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Abstract Case Description An 18‐month‐old spayed female domestic short haired cat was presented for poor appetite, lethargy, exaggerated swallowing, and regurgitation 2 weeks after endoscopic retrieval of gastric foreign material. Clinical Findings The cat was quiet with tacky mucous membranes on physical examination. Point‐of‐care blood testing identified mild azotemia, moderate hypercalcemia, and a sodium‐to‐potassium ratio of 26. An ultrasound examination the next day identified moderate to marked bilateral adrenomegaly. Cytology of a fine needle aspirate of the adrenal glands was consistent with necrosis and associated inflammation. Hypoadrenocorticism was diagnosed by a confirmatory adrenocorticotropic hormone stimulation test. Treatment and Outcome The cat normalized both clinically and biochemically after treatment with prednisolone and desoxycorticosterone pivalate. Clinical Relevance Acute adrenal necrosis has been well documented in human medicine after anesthetic events. To our knowledge, hypoadrenocorticism caused by cytologically confirmed acute adrenal necrosis has not been previously reported in dogs and cats.

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