Nature Communications (Jan 2023)
Projected health impact of post-discharge malaria chemoprevention among children with severe malarial anaemia in Africa
- Lucy C. Okell,
- Titus K. Kwambai,
- Aggrey Dhabangi,
- Carole Khairallah,
- Thandile Nkosi-Gondwe,
- Peter Winskill,
- Robert Opoka,
- Andria Mousa,
- Melf-Jakob Kühl,
- Tim C. D. Lucas,
- Joseph D. Challenger,
- Richard Idro,
- Daniel J. Weiss,
- Matthew Cairns,
- Feiko O. ter Kuile,
- Kamija Phiri,
- Bjarne Robberstad,
- Amani Thomas Mori
Affiliations
- Lucy C. Okell
- MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College
- Titus K. Kwambai
- Centre for Global Health Research (CGHR), Kenya Medical Research Institute (KEMRI)
- Aggrey Dhabangi
- College of Health Sciences, Makerere University
- Carole Khairallah
- Department of Clinical Sciences, Liverpool School of Tropical Medicine (LSTM)
- Thandile Nkosi-Gondwe
- Kamuzu University of Health Sciences
- Peter Winskill
- MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College
- Robert Opoka
- College of Health Sciences, Makerere University
- Andria Mousa
- MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College
- Melf-Jakob Kühl
- Section for Ethics and Health Economics, Department of Global Public Health and Primary Care, University of Bergen
- Tim C. D. Lucas
- Big Data Institute, University of Oxford
- Joseph D. Challenger
- MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College
- Richard Idro
- College of Health Sciences, Makerere University
- Daniel J. Weiss
- Malaria Atlas Project, Telethon Kids Institute, Perth Children’s Hospital
- Matthew Cairns
- International Statistics and Epidemiology Group, London School of Hygiene and Tropical Medicine
- Feiko O. ter Kuile
- Centre for Global Health Research (CGHR), Kenya Medical Research Institute (KEMRI)
- Kamija Phiri
- Kamuzu University of Health Sciences
- Bjarne Robberstad
- Section for Ethics and Health Economics, Department of Global Public Health and Primary Care, University of Bergen
- Amani Thomas Mori
- Section for Ethics and Health Economics, Department of Global Public Health and Primary Care, University of Bergen
- DOI
- https://doi.org/10.1038/s41467-023-35939-w
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 10
Abstract
Trial data have shown that post-discharge malaria chemoprevention (PDMC) reduces the risk of readmission and death in children previously hospitalised with severe malarial anaemia. Here, the authors use mathematical modelling to estimate the potential epidemiological impacts of PDMC in malaria-endemic countries in Africa.
