A brief overview of drug-induced liver damage

Abstract

Abstract Drug-induced liver injury (DILI) is a prevalent disorder that can be led on by almost all drug types. The majority of benign DILI cases become better after drug discontinuation. To stop the development of acute or chronic liver failure, it is crucial to identify and get rid of the offending substance as soon as feasible. DILI does not have any identified risk factors, but certain people may be more susceptible due to genetic vulnerability and previous liver disease. Some patients may exhibit indications of systemic hypersensitivity, even though the majority of patients have clinical symptoms that are the same as those of other liver illnesses. Rapid drug withdrawal and supportive care aimed at reducing uncomfortable symptoms comprise the treatment for drug- and herbal-induced liver damage.

Keywords

• Liver injury
• Drug
• Hypersensitivity
• Toxicity
• Serum biomarkers