Nature Communications (Feb 2021)

Surface-bound reactive oxygen species generating nanozymes for selective antibacterial action

  • Feng Gao,
  • Tianyi Shao,
  • Yunpeng Yu,
  • Yujie Xiong,
  • Lihua Yang

DOI
https://doi.org/10.1038/s41467-021-20965-3
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 18

Abstract

Read online

Nanozymes have been used for antibacterial applications but have potential toxicity to mammalian cells. Here the authors suggest that nanozymes that generate surface bound reactive oxygen species disrupt bacterial cell walls but not mammalian cells walls due to the different particle uptake mechanisms.