Nature Communications (May 2021)
Taxonomic signatures of cause-specific mortality risk in human gut microbiome
- Aaro Salosensaari,
- Ville Laitinen,
- Aki S. Havulinna,
- Guillaume Meric,
- Susan Cheng,
- Markus Perola,
- Liisa Valsta,
- Georg Alfthan,
- Michael Inouye,
- Jeramie D. Watrous,
- Tao Long,
- Rodolfo A. Salido,
- Karenina Sanders,
- Caitriona Brennan,
- Gregory C. Humphrey,
- Jon G. Sanders,
- Mohit Jain,
- Pekka Jousilahti,
- Veikko Salomaa,
- Rob Knight,
- Leo Lahti,
- Teemu Niiranen
Affiliations
- Aaro Salosensaari
- Division of Medicine, Turku University Hospital and University of Turku
- Ville Laitinen
- Department of Computing, University of Turku
- Aki S. Havulinna
- Finnish Institute for Health and Welfare
- Guillaume Meric
- Cambridge Baker Systems Genomics Initiative, Baker Heart and Diabetes Institute
- Susan Cheng
- Division of Cardiology, Brigham and Women’s Hospital
- Markus Perola
- Finnish Institute for Health and Welfare
- Liisa Valsta
- Finnish Institute for Health and Welfare
- Georg Alfthan
- Finnish Institute for Health and Welfare
- Michael Inouye
- Cambridge Baker Systems Genomics Initiative, Baker Heart and Diabetes Institute
- Jeramie D. Watrous
- Departments of Medicine and Pharmacology, University of California San Diego
- Tao Long
- Departments of Medicine and Pharmacology, University of California San Diego
- Rodolfo A. Salido
- Department of Pediatrics, University of California San Diego
- Karenina Sanders
- Department of Pediatrics, University of California San Diego
- Caitriona Brennan
- Department of Pediatrics, University of California San Diego
- Gregory C. Humphrey
- Department of Pediatrics, University of California San Diego
- Jon G. Sanders
- Department of Pediatrics, University of California San Diego
- Mohit Jain
- Departments of Medicine and Pharmacology, University of California San Diego
- Pekka Jousilahti
- Finnish Institute for Health and Welfare
- Veikko Salomaa
- Finnish Institute for Health and Welfare
- Rob Knight
- Department of Pediatrics, University of California San Diego
- Leo Lahti
- Department of Computing, University of Turku
- Teemu Niiranen
- Division of Medicine, Turku University Hospital and University of Turku
- DOI
- https://doi.org/10.1038/s41467-021-22962-y
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 8
Abstract
Gut microbiome composition has a role in health and disease. Here the authors show that microbiome signatures related to the Enterobacteriaceae family are associated with cause-specific mortality risk in a well phenotyped Finish population over a 15-year follow-up.
