Genetic dissection of clonal lineage relationships with hydroxytamoxifen liposomes

Ryan C. Ransom; Deshka S. Foster; Ankit Salhotra; Ruth Ellen Jones; Clement D. Marshall; Tripp Leavitt; Matthew P. Murphy; Alessandra L. Moore; Charles P. Blackshear; Elizabeth A. Brett; Derrick C. Wan; Michael T. Longaker

doi:10.1038/s41467-018-05436-6

Nature Communications (Jul 2018)

Genetic dissection of clonal lineage relationships with hydroxytamoxifen liposomes

Ryan C. Ransom,
Deshka S. Foster,
Ankit Salhotra,
Ruth Ellen Jones,
Clement D. Marshall,
Tripp Leavitt,
Matthew P. Murphy,
Alessandra L. Moore,
Charles P. Blackshear,
Elizabeth A. Brett,
Derrick C. Wan,
Michael T. Longaker

Affiliations

Ryan C. Ransom: Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine
Deshka S. Foster: Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine
Ankit Salhotra: Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine
Ruth Ellen Jones: Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine
Clement D. Marshall: Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine
Tripp Leavitt: Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine
Matthew P. Murphy: Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine
Alessandra L. Moore: Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine
Charles P. Blackshear: Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine
Elizabeth A. Brett: Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine
Derrick C. Wan: Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine
Michael T. Longaker: Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine

DOI: https://doi.org/10.1038/s41467-018-05436-6
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 8

Abstract

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Targeted genetic dissection of tissues can be used to identify cell populations and lineages. Here the authors develop 4-hydroxytamoxifen liposomes for the localized induction of CreERT2.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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