Haemolymph of Cold-Adapted Baikal Endemic Amphipods as a Promising Source for Screening of Novel Natural Products

Axenov-Gribanov D.V.; Protasov E.S.; Voytsekhovskaya I.V.; Shatilina Z.M.; Rzhechitskiy Y.A.; Dimova M.D.; Kostka D.V.; Lubyaga Y.A.; Timofeyev M.A.

Journal of Stress Physiology & Biochemistry (Dec 2017)

Haemolymph of Cold-Adapted Baikal Endemic Amphipods as a Promising Source for Screening of Novel Natural Products

Axenov-Gribanov D.V. ,
Protasov E.S.,
Voytsekhovskaya I.V.,
Shatilina Z.M.,
Rzhechitskiy Y.A.,
Dimova M.D.,
Kostka D.V.,
Lubyaga Y.A.,
Timofeyev M.A.

Affiliations

Axenov-Gribanov D.V.: Baikal Research Centre, Irkutsk, 21 Lenin str., Russia
Protasov E.S.: Institute of Biology at Irkutsk State University, Irkutsk, 3 Lenin str., Russia
Voytsekhovskaya I.V.: Institute of Biology at Irkutsk State University, Irkutsk, 3 Lenin str., Russia
Shatilina Z.M.: Baikal Research Centre, Irkutsk, 21 Lenin str., Russia
Rzhechitskiy Y.A.: Institute of Biology at Irkutsk State University, Irkutsk, 3 Lenin str., Russia
Dimova M.D.: Institute of Biology at Irkutsk State University, Irkutsk, 3 Lenin str., Russia
Kostka D.V.: Institute of Biology at Irkutsk State University, Irkutsk, 3 Lenin str., Russia
Lubyaga Y.A.: Baikal Research Centre, Irkutsk, 21 Lenin str., Russia
Timofeyev M.A.: Institute of Biology at Irkutsk State University, Irkutsk, 3 Lenin str., Russia

Journal volume & issue: Vol. 13, no. 4
pp. 74 – 80

Abstract

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The aim of this study was to assess the possibility to use Baikal endemic amphipods as a source for screening of novel natural products. Analysis of amphipod’s E. verrucosus hemolymph by HPLC-MS was performed for the first time. A number of natural products with new molecular mass for Baikal endemic macroinvertebrates were found. We found a compound as chrysin by comparison of MS1, MS2 profiles and molecular mass of natural products registered in Dictionary of Natural Products and MZ-cloud databases. Also, we found new compound with mass 493.80277 Da, circulating in the amphipod’s hemolymph.

Published in Journal of Stress Physiology & Biochemistry

ISSN: 1997-0838 (Online)
Publisher: "Vikol publishing" ST Kolesnichenko V.V.
Country of publisher: Russian Federation
LCC subjects: Science: Chemistry: Organic chemistry: Biochemistry
Website: http://www.jspb.ru/

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