Journal for ImmunoTherapy of Cancer (Oct 2020)

Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of lymphoma

  • Ronald Levy,
  • Joshua Brody,
  • David L Porter,
  • Sattva S Neelapu,
  • Koen Van Besien,
  • Michael Werner,
  • Michael R Bishop,
  • Mitchell S Cairo,
  • Sherry Adkins,
  • Stephen M Ansell,
  • Jonathan W Friedberg,
  • Justin P Kline

DOI
https://doi.org/10.1136/jitc-2020-001235
Journal volume & issue
Vol. 8, no. 2

Abstract

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The recent development and clinical implementation of novel immunotherapies for the treatment of Hodgkin and non-Hodgkin lymphoma have improved patient outcomes across subgroups. The rapid introduction of immunotherapeutic agents into the clinic, however, has presented significant questions regarding optimal treatment scheduling around existing chemotherapy/radiation options, as well as a need for improved understanding of how to properly manage patients and recognize toxicities. To address these challenges, the Society for Immunotherapy of Cancer (SITC) convened a panel of experts in lymphoma to develop a clinical practice guideline for the education of healthcare professionals on various aspects of immunotherapeutic treatment. The panel discussed subjects including treatment scheduling, immune-related adverse events (irAEs), and the integration of immunotherapy and stem cell transplant to form recommendations to guide healthcare professionals treating patients with lymphoma.